| Title Transcription | インターフェロン アルファ リョウホウゴ タゾウキ フゼン ニテ シボウ シタ マンセイ コツズイセイ ハッケツビョウ ノ ボウケンレイ
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| Title Alternative (English) | A case of Multi-organ Failure Associated with Interferone-α (IFN-α) Therapy for Chronic Myelocytic Leukemia (CML)
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| File | |
| language |
jpn
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| Author |
Doi, Takashi
Torii, Ikuko
Morikawa, Shigeru
Kobayashi, Shotai
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| Description | Interferone-α is used recently in the treatment of hematologic malignancies as well as viral hepatitis. Occurrences of various adverse effects associated with IFN have been reported increasingly. We report here in a case of patient who developed diverse clinical symptoms in various organs such as heart, liver, kidney following long-term IFN therapy for chronic myelocytic leukemia. The autopsy revealed the pathological changes in various tissues such as the heart muscles, the renal glomeruli and the skeletal muscles, which were confirmed by transmitted electron microscopy. The possible roles of IFN-α in those tissue damages are discussed.
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| Subject | インターフェロン-α
慢性骨髄性白血病
多臓器不全
IFN-α
C. M. L.
multi-organ failure
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| Journal Title |
Bulletin of Shimane Medical University
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| Volume | 21
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| Start Page | 45
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| End Page | 50
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| ISSN | 03879097
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| Published Date | 1998-12-01
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| NCID | AN00107602
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| Publisher | 島根医科大学
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| NII Type |
Departmental Bulletin Paper
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| Format |
PDF
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| Text Version |
出版社版
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| OAI-PMH Set |
Faculty of Medicine
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| 他の一覧 |
