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File
language
eng
Attribute
Technical note
Author
Yamamoto, Yasushi Department of Radiology, Shimane University Hospital
Nishiyama, Yuichi Department of Radiology
Haramoto, Masuo Department of Radiology, Shimane University Hospital
Sota, Takumi Shimane Prefectural Central Hospital
Miyai, Masahiro Department of Radiology, Shimane University Hospital
Uchibe, Taku Department of Radiology, Shimane University Hospital
Yada, Nobuhiro Department of Radiology, Shimane University Hospital
Nishiyama, Yukako Department of Radiology, Shimane University Hospital
Kitagaki, Hajime Department of Radiology
Description
This study examined the utility of cadmium-zinctelluride (CZT) semiconductor camera for quantifying striatal tracer uptake in single-photon emission computed tomography (SPECT) with 123I-ioflupane (DaTSCAN). An anthropomorphic striatal phantom was prepared with 123I-ioflupane. The phantom images were obtained using a CZT camera and a traditional Anger-type camera for 5 min and 30 min, respectively. Phantom image quality was visually evaluated, and the contrast between the striatal and cerebral parenchyma (background region) was examined via count profile analysis. Then, the specific binding ratio (SBR), which indicates 123I uptake in the striatum, was measured. There were no visual differences in striatal shape between the scans, but the CZT/SPECT scan exhibited better image contrast. The SBR obtained from the CZT/SPECT images were higher than those acquired from the Anger/SPECT images and were closer to the true values. Performing CZT/SPECT using DaTSCAN might enable more accurate evaluations of striatal function while reducing the imaging time.
Subject
dopamine transporter
single-photon emission computed tomography
cadmium zinc telluride
phantom study
Journal Title
Shimane Journal of Medical Science
Volume
34
Issue
1
Start Page
35
End Page
40
ISSN
03865959
ISSN(Online)
24332410
Published Date
2017-07-31
NCID
AA00841586
Publisher
Faculty of Medicine, Shimane University
Publisher Aalternative
島根大学医学部
NII Type
Departmental Bulletin Paper
Format
PDF
Rights
Faculty of Medicine, Shimane University
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
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