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language
eng
Attribute
Review
Author
Hisamatsu, Takashi Department of Environmental Medicine and Public Health
Description
Atherosclerotic cardiovascular disease (ASCVD),including coronary heart disease, remains a major cause of death and disability among developed countries. Coronary artery calcification (CAC), which is detected by computed tomography scanning, is a well-known measure of subclinical atherosclerosis. CAC is considered to have important implications for understanding the long-term accumulated burden of cardiovascular risk factors and for the possibility of reclassification at the preclinical phase for preventing ASCVD. This review focuses on CAC and its usability in primary prevention of ASCVD. Numerous epidemiological studies, mainly in Western countries, have indicated that, among asymptomatic individuals, the CAC score is associated with future ASCVD. Additionally, the CAC score provides improved predictive values for estimating the risk of ASCVD beyond traditional cardiovascular risk factors. However, a lack of evidence for this score in other populations warrants further investigations. Clinical trials are also necessary to demonstrate the usefulness and safety of CAC screening for primary prevention of ASCVD.
Subject
atherosclerotic cardiovascular disease
coronary artery calcification
primary prevention
epidemiology
Journal Title
Shimane Journal of Medical Science
Volume
34
Issue
1
Start Page
1
End Page
5
ISSN
03865959
ISSN(Online)
24332410
Published Date
2017-07-31
NCID
AA00841586
Publisher
Faculty of Medicine, Shimane University
Publisher Aalternative
島根大学医学部
NII Type
Departmental Bulletin Paper
Format
PDF
Rights
Faculty of Medicine, Shimane University
Text Version
出版社版
OAI-PMH Set
Faculty of Medicine
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